The European Journal of Clinical Pharmacology publishes original papers, short communications, and letters to the editors on all aspects of clinical pharmacology and drug therapy in humans. Coverage includes therapeutic trials; pharmacokinetics; drug metabolism; adverse drug reactions; drug interactions; all aspects of drug development; prescribing policies; pharmacoepidemiology; and matters relating to the safe use of drugs. Data from animal experiments are published only in the context of parallel experiments in man reported in the same paper. The journal also publishes review articles on special problems related to these areas, and encourages debate on controversial issues.